0000001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 0000002 - Document - Audit Information link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - CONSOLIDATED BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - CONSOLIDATED STATEMENTS OF OPERATIONS link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY link:presentationLink link:calculationLink link:definitionLink 9952156 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952157 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Organization and Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Revenues link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Fair Value of Financial Instruments link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Concentrations of Credit Risk and Current Expected Credit Losses link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Acquisitions link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Inventory link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Collaborative and Other Relationships link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Property and Equipment, net link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Intangible Assets and Goodwill link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Accrued and Other Current Liabilities link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Stockholders' Equity link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Stock Compensation link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Other Comprehensive Income (Loss) link:presentationLink link:calculationLink link:definitionLink 9952171 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 9952172 - Disclosure - Net Income Per Share link:presentationLink link:calculationLink link:definitionLink 9952173 - Disclosure - Employee Benefit Plans link:presentationLink link:calculationLink link:definitionLink 9952174 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952175 - Disclosure - Segment Information link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Organization and Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Revenues (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Fair Value of Financial Instruments (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Concentrations of Credit Risk and Current Expected Credit Losses (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Acquisitions (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Inventory (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Property and Equipment, net (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Intangible Assets and Goodwill (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Accrued and Other Current Liabilities (Tables) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Stockholders' Equity (Tables) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Stock Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Other Comprehensive Income (Loss) (Tables) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Income Taxes (Tables) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Net Income Per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Employee Benefit Plans (Tables) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Segment Reporting (Tables) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Organization and Summary of Significant Accounting Policies (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Revenues (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Fair Value of Financial Instruments - Schedule of Marketable Securities Portfolio (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Fair Value of Financial Instruments - Schedule of Contractual Maturities of Our Available-For-Sale Debt Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Fair Value Measures and Disclosures - Schedule of Assets Measured on a Recurring Basis (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Fair Value Measures and Disclosures - Schedule of Liabilities Measured on a Recurring Basis (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Fair Value Measures and Disclosures - Schedule of Level 3 Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Fair Value Measures and Disclosures - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Concentration of Credit Risk and Current Expected Credit Losses - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Concentrations of Credit Risk and Current Expected Credit Losses - Schedule of Concentration of Credit Risk Related to Collaborative Partners (Details) (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Acquisitions - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Acquisitions - Schedule of Net of Compensation Expense, Across the Net Assets Acquired (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Inventory - Schedule of Inventory Balances (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Inventory - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Collaborative and Other Relationships - Novartis (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Collaborative and Other Relationships - Lily (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Collaborative and Other Relationships - Agenus (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Collaborative and Other Relationships - Merus (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Collaborative and Other Relationships - MacroGenics (Details) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - Collaborative and Other Relationships - MorphoSys (Details) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - Collaborative and Other Relationships - Syndax (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Collaborative and Other Relationships - Prelude (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - Property and Equipment, net - Schedule of Property and Equipment, Net (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - Property and Equipment, net - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955551 - Disclosure - Property and Equipment, net - Schedule of Lease and Maturity of Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955552 - Disclosure - Intangible Assets and Goodwill (Details) link:presentationLink link:calculationLink link:definitionLink 9955553 - Disclosure - Accrued and Other Current Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955554 - Disclosure - Stockholders' Equity - 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Disclosure - Income Taxes - Schedule of Income Before Provision (Details) link:presentationLink link:calculationLink link:definitionLink 9955563 - Disclosure - Income Taxes - Schedule of Provision for Income Taxes (Details) link:presentationLink link:calculationLink link:definitionLink 9955564 - Disclosure - Income Taxes - Schedule of Income Taxes Paid, Net of (Refunds) Received (Details) link:presentationLink link:calculationLink link:definitionLink 9955565 - Disclosure - Income Taxes - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955566 - Disclosure - Income Taxes - Schedule of Effective Income Tax Rate (Details) link:presentationLink link:calculationLink link:definitionLink 9955567 - Disclosure - Income Taxes - Schedule of Reconciliation of Income Taxes (Details) link:presentationLink link:calculationLink link:definitionLink 9955568 - Disclosure - Income Taxes - Schedule of Tax Credit Carryforwards (Details) link:presentationLink link:calculationLink link:definitionLink 9955569 - Disclosure - Income Taxes - Schedule of Unrecognized Tax Benefits (Details) link:presentationLink link:calculationLink link:definitionLink 9955570 - Disclosure - Net Income Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955571 - Disclosure - Employee Benefit Plans - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955572 - Disclosure - Employee Benefit Plans - Schedule of Defined Benefit Pension Plan (Details) link:presentationLink link:calculationLink link:definitionLink 9955573 - Disclosure - Employee Benefit Plans - Schedule of Net Periodic Benefit Cost (Details) link:presentationLink link:calculationLink link:definitionLink 9955574 - Disclosure - Employee Benefit Plans - Schedule of Expected Benefit Payments (Details) link:presentationLink link:calculationLink link:definitionLink 9955575 - Disclosure - Commitments and contingencies - Commitments (Details) link:presentationLink link:calculationLink link:definitionLink 9955576 - Disclosure - Commitments and contingencies - Contingencies (Details) link:presentationLink link:calculationLink link:definitionLink 9955577 - Disclosure - Segment Information - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955578 - Disclosure - Segment Reporting - Schedule of Consolidated Net Income (Details) link:presentationLink link:calculationLink link:definitionLink 9955579 - Disclosure - Segment Reporting - Schedule of Long-Lived Assets by Geographic Areas (Details) link:presentationLink link:calculationLink link:definitionLink 9955580 - Disclosure - Segment Reporting - Schedule of Property and Equipment, Net by Geographic Areas (Details) link:presentationLink link:calculationLink link:definitionLink