PROSPECTUS SUPPLEMENT                           FILED PURSUANT TO RULE 424(B)(3)
TO PROSPECTUS DATED AUGUST 2, 2000                    REGISTRATION NO. 333-36318

                                  $200,000,000

                             INCYTE GENOMICS, INC.

                  5.5% CONVERTIBLE SUBORDINATED NOTES DUE 2007
                                      AND
                             SHARES OF COMMON STOCK
                     ISSUABLE UPON CONVERSION OF THE NOTES

     This prospectus supplement relates to the resale by the holders of 5.5%
convertible subordinated notes due 2007 of Incyte Genomics, Inc. and the shares
of common stock issuable upon conversion of the notes.

     This prospectus supplement should be read in conjunction with the
prospectus dated August 2, 2000, which is to be delivered with this prospectus
supplement.

     The information in the table appearing under the heading "Selling
Securityholders" in the prospectus is supplemented and superseded in part by the
information appearing in the table below:




                                                      Principal Amount
                                                          of Notes           Common Stock                            Common Stock
                                                        Beneficially         Issuable Upon                           Owned After
                                                          Owned and            Conversion         Common Stock        Completion
                      NAME                                Offered(1)         of the Notes(1)        Offered(1)      the Offering(1)
                      ----                            ----------------       ---------------      ------------      ---------------
                                                                                                              

 Onyx Fund Holdings, LDC.........................       $13,500,000             100,119               100,119             -



                             ----------------------

(1)  Amounts indicated may be in excess of the total amount registered due
     to sales or transactions exempt from the registration requirements of
     the Securities Act of 1933 since the date on which selling
     securityholders provided information to us regarding their notes.

     None of the selling securityholders listed above nor any of their
     affiliates, officers, directors or principal equity holders has held
     any position or office or has had any material relationship with us
     within the past three years.

                              --------------------

     INVESTING IN THE NOTES AND OUR COMMON STOCK INVOLVES A HIGH DEGREE OF
RISK. YOU SHOULD CAREFULLY READ AND CONSIDER THE "RISK FACTORS" BEGINNING ON
PAGE 3 OF THE PROSPECTUS.

                              --------------------

     Neither the Securities and Exchange Commission nor any state securities
commission has approved or disapproved of these securities or passed upon the
accuracy or adequacy of this prospectus supplement or the prospectus. Any
representation to the contrary is a criminal offense.

                              --------------------

           The date of this Prospectus Supplement is August 25, 2000.