AS  FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON OCTOBER 27, 1998
REGISTRATION  NO.  333-57119


SECURITIES  AND  EXCHANGE  COMMISSION
WASHINGTON,  D.C.  20549
_______________
POST-EFFECTIVE  AMENDMENT  NO.  1
TO
FORM  S-3
REGISTRATION  STATEMENT
UNDER
THE  SECURITIES  ACT  OF  1933
_______________

INCYTE  PHARMACEUTICALS,  INC.
(Exact  name  of  registrant  as  specified  in  its  charter)
Delaware                                           94-3136539
(State or other jurisdiction of 
incorporation or organization)             (I.R.S.Employer Identification No.)
3174  Porter  Drive
Palo  Alto,  California  94304
(650)  855-0555
(Address,  including zip code, and telephone number, including area code,
of  registrant's  principal  executive  offices)

ROY  A.  WHITFIELD
Chief  Executive  Officer
Incyte  Pharmaceuticals,  Inc.
3174  Porter  Drive
Palo  Alto,  California  94304
(650)  855-0555
(Name,  address, including zip code, and telephone number, including area
code,  of  agent  for  service)

Copies  to:

STANTON  D.  WONG
SALLY  BRAMMELL
Pillsbury Madison & Sutro LLP
P.O. Box 7880
San Francisco, California 94120

_______________





     TERMINATION  OF  REGISTRATION

Incyte  Pharmaceuticals,  Inc. (the "Registrant") hereby removes and withdraws
from  registration  922,987  shares  of  Common Stock, $.001 par value, of the
Registrant.  The Shares were unsold at the termination of the offering covered
by  this  Registration  Statement.



     SIGNATURES

Pursuant  to  the  requirements  of the Securities Act of 1933, the Registrant
certifies  that  it has reasonable grounds to believe that it meets all of the
requirements  for  filing  on  Form
S-3  and  has  duly caused this Post-Effective Amendment No. 1 to be signed on
its  behalf  by the undersigned, thereunto duly authorized in the City of Palo
Alto,  State  of  California,  on  October  27,  1998.

                                             INCYTE  PHARMACEUTICALS,  INC.



                                             By    /s/ Denise M. Gilbert
                                                   ---------------------
                                                   Denise  M.  Gilbert
                                                   Executive  Vice President  
                                                   and  CFO




Pursuant  to  the  requirements  of  the  Securities  Act, this Post-Effective
Amendment  No.  1  to  the Registration Statement has been signed below by the
following  persons  in  the  capacities  and  on  the  dates  indicated.
Name Title Date - - --------------------- ------------------------------- ---------------- Chief Executive Officer October 27, 1998 * (Principal Executive Officer) - - --------------------- and Director Roy A. Whitfield Executive Vice President and October 27, 1998 * Chief Financial Officer - - --------------------- (Principal Financial Officer) Denise M. Gilbert Controller * (Principal Accounting Officer) October 27, 1998 - - --------------------- William Delaney * Chairman of the Board October 27, 1998 - - --------------------- Jeffrey J. Collinson * Director October 27, 1998 - - --------------------- Barry M. Bloom October 27, 1998 * Director - - --------------------- Frederick B. Craves October 27, 1998 * Director - - --------------------- Jon S. Saxe October 27, 1998 * Director - - --------------------- Randal W. Scott
* By: /s/ Denise M. Gilbert ------------------------ Denise M. Gilbert Attorney-in-Fact